July 16, 2024

Engineers on the Massachusetts Institute of Know-how (MIT) are shaking issues up on this planet of weight problems remedies: They’ve developed an ingestible capsule that vibrates contained in the abdomen.

The vibrations from the capsule, named the Vibrating Ingestible BioElectronic Stimulator (VIBES), create an phantasm of being full by activating the identical mind receptors your abdomen sends alerts to when it’s stretched, in accordance with the engineers. 

The oral capsule is concerning the measurement of a multivitamin and is powered by a small silver oxide battery. As soon as it’s swallowed and it reaches the abdomen, acidic gastric fluids dissolve a gelatinous membrane that covers the capsule, finishing the digital circuit that prompts the vibrating motor inside. 

MIT stated the present model of the capsule is designed to vibrate for about half-hour after it reaches the abdomen, however the researchers plan to discover the potential for adapting it to stay within the abdomen for longer intervals, the place it may very well be turned on and off wirelessly as wanted. 

“For any person who needs to drop a few pounds or management their urge for food, it may very well be taken earlier than every meal,” stated Dr. Shriya Srinivasan, an MIT graduate who’s now an assistant professor of bioengineering at Harvard College. “This may very well be actually fascinating in that it could present an possibility that would reduce the uncomfortable side effects that we see with the opposite pharmacological remedies on the market.”

Srinivasan is the lead writer of the examine on the vibrating capsule, which was revealed in Science Advances.

In animals who got the vibrating capsule 20 minutes earlier than consuming, the researchers discovered that this therapy not solely stimulated the discharge of hormones that sign the sensation of fullness but additionally lowered the animals’ meals consumption by about 40%, in accordance with MIT. 

The capsules handed via the digestive tract of the animals used within the examine inside 4 to 5 days. Researchers famous the animals didn’t present any indicators of obstruction, perforation or different unfavourable impacts whereas the capsule was of their digestive tract. 

Whereas scientists have extra to study and haven’t examined the impacts in people, such a know-how may supply a minimally invasive method to deal with weight problems compared to bariatric surgical procedure or weight reduction medicine available on the market like Zepbound and Wegovy, the researchers stated.

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